Basic Information

Symbol
hsa-mir-33b
RNA class
miRNA miRNA hairpin
Alias
MIR33B MicroRNA 33b Hsa-MiR-33b-5p Hsa-MiR-33b-3p Hsa-Mir-33b MIRN33B Hsa-Mir-33-P1_pre MIMAT0003301 MIMAT0004811 MI0003646 Mir-33b
Location (GRCh38)
19:53742512-53742599
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-33b
Sequence length
96 nt
GC content
0.7292

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-60.20 kcal/mol
Thermodynamic ensemble
Free energy: -61.49 kcal/mol
Frequency: 0.1242
Diversity: 6.07
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((((.(((.((((((((((((..(((((((((.(((.....))).)))))))))..)))))))))).))))).))).))))...)).....
Thermodynamic Ensemble Prediction
(((((((((.(((.((((((((((((..(((((((((.(((.....))).)))))))))..)))))))))).))))).)))},)))...}).....
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-33b was profiled in the prefrontal cortex of depressed suicide completers and psychiatrically healthy controls, but no significant dysregulation was reported in this cohort [Lopez et al. DOI:10.1017/S1461145713000941].