Basic Information

Symbol
hsa-mir-330
RNA class
miRNA miRNA hairpin
Alias
MIR330 MicroRNA 330 Hsa-MiR-330-3p Hsa-MiR-330-5p Hsa-Mir-330 MIRN330 Hsa-Mir-330-V1_pre Hsa-Mir-330-V2_pre MIMAT0000751 MIMAT0004693 MI0000803 Mir-330
Location (GRCh38)
19:45638994-45639087
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Cause of death analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-330
Sequence length
94 nt
GC content
0.6064

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-46.90 kcal/mol
Thermodynamic ensemble
Free energy: -47.87 kcal/mol
Frequency: 0.2058
Diversity: 6.97
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
....(((((.(.(((((((((((((((((((,(((..((((.,...........)))).))))))).))))..))))))))))).).)).))).
Forensic Context

A study in humans demonstrated that a combination of circulating miR-744-3p, miR-324-3p, and miR-330-3p was significantly upregulated in patients with plaque rupture compared to those with plaque erosion, with a diagnostic model achieving an area under the ROC curve of 0.768 in an independent test set [Li et al. DOI:10.1016/j.ygeno.2020.11.019]. In a separate human study, hsa-miR-330-5p was identified as part of a competing endogenous RNA regulatory network predicted to interact with core prognostic mRNA biomarkers CD247, IL2RB, and TGFBR3 in sepsis [Zhang et al. DOI:10.1186/s12920-023-01460-8].