Basic Information

Symbol
hsa-mir-34a
RNA class
miRNA miRNA hairpin
Alias
MIR34A MicroRNA 34a Hsa-MiR-34a-5p Hsa-MiR-34a-3p Hsa-Mir-34a MIRN34A Hsa-Mir-34-P1_pre MIMAT0000255 MIMAT0004557 MI0000268 MiRNA34A Mir-34a Mir-34
Location (GRCh38)
1:9151668-9151777
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-34a
Sequence length
110 nt
GC content
0.5091

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-47.20 kcal/mol
Thermodynamic ensemble
Free energy: -48.79 kcal/mol
Frequency: 0.0761
Diversity: 5.98
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((.(((((((((((((((..(((((((((((.((((((((((....((....)).....))))))))))))).))))))))..))))))))).))))..))..)))).
Thermodynamic Ensemble Prediction
((((.(({(((((({(((((..(((((((((((.((((((((((.,..((....))..,..))))))))))))).))))))))..)))))}))).))))..))..)))).
Forensic Context

A study in mice demonstrated that the mir-34a is induced by ionizing radiation in a p53-dependent manner across multiple organs and is detectable and stable in serum for up to 48 hours post-exposure, with higher induction levels in young mice correlating with greater radio-sensitivity [Liu et al. DOI:10.7150/ijbs.7.221].