Basic Information

Symbol
hsa-miR-34c-3p
RNA class
miRNA mature miRNA
Alias
hsa-miR-34c MIR34C MicroRNA 34c
Location (GRCh38)
-
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-34c-3p
Sequence length
22 nt
GC content
0.5455
Forensic Context

A study in humans demonstrated that the miR-34c-3p is upregulated in venous ulcers compared to normal skin and acute wounds [Siu et al. DOI:10.1111/wrr.13100]. A study in rats demonstrated that the miR-34c-3p in plasma exosomes showed a decreasing trend over time following acute myocardial infarction (AMI) [Zhou et al. DOI: 10.007/s00414-025-03583-2]. In a mouse model of AMI, the miR-34c-3p was significantly downregulated in infarcted myocardial tissue and was predicted to target heart rate-related genes Cacna1e and Ank2 [Tuerxun et al. DOI: 10.1007/s12013-024-01528-x].