Basic Information

Symbol
hsa-mir-340
RNA class
miRNA miRNA hairpin
Alias
MIR340 MicroRNA 340 Hsa-MiR-340-5p Hsa-MiR-340-3p Hsa-Mir-340 MIRN340 Hsa-Mir-340_pre MIMAT0000750 MIMAT0004692 MI0000802 Mir-340
Location (GRCh38)
5:180015303-180015397
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Sudden cardiac death diagnosis Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-340
Sequence length
95 nt
GC content
0.3895

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.80 kcal/mol
Thermodynamic ensemble
Free energy: -37.02 kcal/mol
Frequency: 0.1391
Diversity: 3.79
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((((.((((((.((((((((...((((((.((((.(((((.......))))))))).))))))....)))))))).)))))).)))))....
Thermodynamic Ensemble Prediction
..(((((.((((((.((((((((.,,((((((.((((.{((((.......))))})))).)))))).,,.)))))))).)))))).)))))....
Forensic Context

A study in humans with coronary artery disease identified the mir-340 as differentially expressed in whole blood between patients with and without recurrent myocardial infarction in both initial and replication cohorts, though its specific direction of association was not detailed [Onuoha et al. DOI:10.1111/cts.13307]. In a separate review of human skin biology, the mir-340 was found to be upregulated 24 hours post-injury in skin wounds compared to unwounded skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans identified the mir-340 as an absolute specific marker (ASM) for venous blood, demonstrating high specificity across all pairwise comparisons and confirming its utility for body fluid identification in forensic stains [Liu et al. DOI:10.3390/genes13091530].