Basic Information

Symbol
hsa-mir-345
RNA class
miRNA miRNA hairpin
Alias
MIR345 MicroRNA 345 Hsa-MiR-345-5p Hsa-Mir-345 MIRN345 Hsa-Mir-345_pre Hsa-MiR-345-3p MIMAT0022698 MIMAT0000772 MI0000825 Mir-345
Location (GRCh38)
14:100307859-100307956
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-345
Sequence length
98 nt
GC content
0.6020

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-51.90 kcal/mol
Thermodynamic ensemble
Free energy: -52.86 kcal/mol
Frequency: 0.2106
Diversity: 2.89
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...(((((((.((((((.(.(((((((.((.((((((((((........)))))))))).)).))))))).).)))))))))))))............
Thermodynamic Ensemble Prediction
...(((((((.((((((.(.(((((((.((.((((((((((.,....,.}))))))))).)).))))))).).)))))))))))))............
Forensic Context

A study in severely injured human patients identified 69 differentially expressed miRNAs, including the mir-345 which showed an indirect correlation with total fresh frozen plasma transfused [Uhlich et al. DOI:10.1016/j.surg.2014.06.017]. In a rat model of cavernous nerve injury erectile dysfunction, high-throughput sequencing identified rno-miR-345-5p_R+1 as a differentially expressed miRNA, and it was predicted to be sponged by the downregulated circRNA945 [Huang et al. DOI:10.1080/21655979.2021.1973863].