Forensic Context

A study in severely injured human patients identified 69 differentially expressed miRNAs, including the mir-345 which showed an indirect correlation with total fresh frozen plasma transfused [Uhlich et al. DOI:10.1016/j.surg.2014.06.017]. In a rat model of cavernous nerve injury erectile dysfunction, high-throughput sequencing identified rno-miR-345-5p_R+1 as a differentially expressed miRNA, and it was predicted to be sponged by the downregulated circRNA945 [Huang et al. DOI:10.1080/21655979.2021.1973863].