Basic Information

Symbol
hsa-mir-346
RNA class
miRNA miRNA hairpin
Alias
MIR346 MicroRNA 346 Hsa-Mir-346 Hsa-MiR-346 MIRN346 Hsa-Mir-346_pre MIMAT0000773 MI0000826 MiRNA346 MiR-346
Location (GRCh38)
10:86264694-86264788
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden death from respiratory system disease Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-346
Sequence length
95 nt
GC content
0.6737

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-48.10 kcal/mol
Thermodynamic ensemble
Free energy: -49.96 kcal/mol
Frequency: 0.5407
Diversity: 2.38
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(.((((((..((((((.((((..((((((...((((((((.((..........)))))))))).)).))))..)))).)))))).)))))))..
Thermodynamic Ensemble Prediction
.(.((((((.{{(((((.((((..((((({...((((((((,((..........)))))))))).)},))))..)))).)))))).)))))))..
Forensic Context

A study in humans identified the mir-346 as a potential biomarker predicted to bind hsa_circRNA_104161, a circRNA that was upregulated in lung tissue and plasma from sepsis-induced ARDS patients [Guo et al. DOI:10.1016/j.lfs.2021.119566]. A review of human postmortem brain studies found that the mir-346 is downregulated in the Brodmann area 46 of subjects with schizophrenia and is located in intron 2 of the GRID1 gene [Yoshino & Dwivedi DOI:10.3389/fpsyt.2020.543893].