Basic Information

Symbol
hsa-mir-361
RNA class
miRNA miRNA hairpin
Alias
MIR361 MicroRNA 361 Hsa-MiR-361-5p Hsa-MiR-361-3p Hsa-Mir-361 MIRN361 Hsa-Mir-361-V1_pre Hsa-Mir-361-V2_pre MIMAT0004682 MIMAT0000703 MI0000760 Mir-361
Location (GRCh38)
X:85903636-85903707
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-361
Sequence length
72 nt
GC content
0.4167

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-31.40 kcal/mol
Thermodynamic ensemble
Free energy: -31.89 kcal/mol
Frequency: 0.4539
Diversity: 2.94
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in severely injured human patients demonstrated that the mir-361 showed an indirect correlation with total fresh frozen plasma transfused [Uhlich et al. DOI:10.1016/j.surg.2014.06.017]. Another study in human trauma patients found that hsa-miR-361-3p was more abundant in injury-stage T cells compared to recovery stage according to NGS, though it was not significantly upregulated in RT-qPCR validation [Rau et al. DOI:10.2147/JIR.S375881]. In a separate human study, a different isoform, miR-361-3p, was found to be significantly up-regulated in the serum of patients with obstructive sleep apnea syndrome compared to healthy controls [Mo et al. DOI:10.2147/NSS.S382765].