Basic Information

Symbol
hsa-mir-3611
RNA class
miRNA miRNA hairpin
Alias
MIR3611 MicroRNA 3611 Hsa-Mir-3611 Hsa-MiR-3611 Hsa-Mir-3611_pre MIMAT0017988 MI0016001
Location (GRCh38)
10:35079598-35079680
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3611
Sequence length
83 nt
GC content
0.2651

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-31.10 kcal/mol
Thermodynamic ensemble
Free energy: -32.86 kcal/mol
Frequency: 0.0580
Diversity: 4.31
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
((((({.(((.(((((((((((,.,(((((((((((.,...........))))))))))))))))))))))).))).})))))
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns validated in human skin tissue and cell lines using qRT-PCR, microarrays, and next-generation sequencing [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-3611 was differentially expressed and shared across two pairs of monozygotic twins, with microarray analysis of blood samples from 18 twin pairs identifying 545 differentially expressed miRNAs, including this biomarker, and subsequent qRT-PCR validation on selected miRNAs showing consistent expression patterns [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].