Basic Information
Symbol
hsa-miR-3611
RNA class
miRNA
mature miRNA
Alias
hsa-miR-3611
MIR3611
MicroRNA 3611
Location (GRCh38)
-
Forensic tag(s)
Wound age identification
Individual identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-31.10 kcal/mol
Thermodynamic ensemble
Free energy:
-32.86 kcal/mol
Frequency:
0.0580
Diversity:
4.31
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
((((({.(((.(((((((((((,.,(((((((((((.,...........))))))))))))))))))))))).))).})))))
Forensic Context
A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns validated in human skin tissue and cell lines using qRT-PCR, microarrays, and next-generation sequencing [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the miR-3611 was differentially expressed and shared across two pairs of monozygotic twins, with microarray analysis of blood samples from 18 twin pairs identifying 545 differentially expressed miRNAs, including this biomarker, and subsequent qRT-PCR validation on selected miRNAs showing consistent expression patterns [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].