Basic Information
Symbol
hsa-miR-3615
RNA class
miRNA
mature miRNA
Alias
hsa-miR-3615
MIR3615
MicroRNA 3615
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
Drug abuse diagnoses
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-45.40 kcal/mol
Thermodynamic ensemble
Free energy:
-46.36 kcal/mol
Frequency:
0.2109
Diversity:
2.86
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((.(.((.((((..((.((((((.(((((.((((..((........))..)))).))))).))))))))..)))).)).).))))
Thermodynamic Ensemble Prediction
((((.(.((.((((..((.((((((.(((((.((((..((.,....,.))..)))).))))).))))))))..)))).)).).))))
Forensic Context
A study in humans demonstrated that plasma exosomal hsa-miR-3615, identified as a high-abundance miRNA, exhibited a downregulated expression pattern from healthy controls to coronary artery disease patients to acute myocardial infarction patients, and was part of an 18-miRNA panel that achieved an area under the curve of 0.87 for diagnosing acute myocardial infarction [Guo et al. DOI:10.21037/atm-20-2337]. A study in humans with alcohol use disorders demonstrated that the miR-3615 was increased by 56.4% in serum and was identified as a Tier B biomarker of AUD [Ignacio et al. DOI:10.1186/S12868-015-0195-X].