Basic Information

Symbol
hsa-mir-3616
RNA class
miRNA miRNA hairpin
Alias
MIR3616 MicroRNA 3616 Hsa-Mir-3616 Hsa-MiR-3616-5p Hsa-MiR-3616-3p MIMAT0017995 MIMAT0017996 MI0016006 Mir-3616
Location (GRCh38)
17:80419418-80419493
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3616
Sequence length
92 nt
GC content
0.5435

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-55.60 kcal/mol
Thermodynamic ensemble
Free energy: -57.30 kcal/mol
Frequency: 0.0631
Diversity: 4.18
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((((((((.((((((((((((((.(((.(((((((((.........))))))))).))).)))))))))))))).))))))).)))))
Thermodynamic Ensemble Prediction
{(((((((((((.((((((((((((((.(((.(((((((((,{......,))))))))).))).)))))))))))))).))))))),,)))}
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific dysregulation patterns observed in human skin tissue samples and cell lines post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that miRNA expression profiles can distinguish monozygotic twins, with 545 miRNAs differentially expressed across seven twin pairs, and validation by qRT-PCR confirmed differential expression for select miRNAs including the mir-3616-3p [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].