Basic Information

Symbol
hsa-mir-3619
RNA class
miRNA miRNA hairpin
Alias
MIR3619 MicroRNA 3619 Hsa-MiR-3619-5p Hsa-MiR-3619-3p Hsa-Mir-3619 Hsa-Mir-3619_pre MIMAT0019219 MIMAT0017999 MI0016009
Location (GRCh38)
22:46091044-46091126
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3619
Sequence length
83 nt
GC content
0.6506

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-48.90 kcal/mol
Thermodynamic ensemble
Free energy: -50.38 kcal/mol
Frequency: 0.0903
Diversity: 5.08
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((.(((((((.(((((((((((((.((((.(..(((.....)))).)))).))))))))))).)).)))))))..)))))
Thermodynamic Ensemble Prediction
(((((.(((((((.({(((((((((((.((((.(..(((,...,)))}.)))).))))))))))).)}.)))))))..)))))
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific dysregulation patterns observed in human skin tissue and cell lines post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the mir-3619 suppresses the expression of KCNH2 mRNA and protein, which is associated with long QT syndrome and sudden unexplained cardiac death [Lou et al. DOI:10.1016/j.jflm.2022.102332].