Basic Information

Symbol
hsa-miR-3619-5p
RNA class
miRNA mature miRNA
Alias
hsa-miR-3619 MIR3619 MicroRNA 3619
Location (GRCh38)
-
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database

Sequence & Structure

Transcript ID
hsa-miR-3619-5p
Sequence length
22 nt
GC content
0.6818
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific dysregulation patterns observed in human skin tissue and cell lines post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the mir-3619 suppresses the expression of KCNH2 mRNA and protein, which is associated with long QT syndrome and sudden unexplained cardiac death [Lou et al. DOI:10.1016/j.jflm.2022.102332].