Basic Information

Symbol
hsa-mir-3621
RNA class
miRNA miRNA hairpin
Alias
MIR3621 MicroRNA 3621 Hsa-Mir-3621 MIMAT0018002 Hsa-MiR-3621 MI0016012
Location (GRCh38)
13:92490163-92490220
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3621
Sequence length
85 nt
GC content
0.7294

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-41.00 kcal/mol
Thermodynamic ensemble
Free energy: -41.83 kcal/mol
Frequency: 0.2615
Diversity: 11.80
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans with coronary artery disease identified the mir-3621 as a biomarker for recurrent myocardial infarction risk, where it was downregulated in whole blood of patients with recurrent MI compared to those without, remaining significant after false discovery rate correction (FDR <0.1) in a replication cohort, though it was not significantly different in plasma samples [Onuoha et al. DOI:10.1111/cts.13307].