Basic Information

Symbol
hsa-mir-3658
RNA class
miRNA miRNA hairpin
Alias
MIR3658 MicroRNA 3658 Hsa-Mir-3658 MIMAT0018078 Hsa-MiR-3658 MI0016058
Location (GRCh38)
Forensic tag(s)
Wound age identification Individual identification

Sequence & Structure

Transcript ID
hsa-mir-3658
Sequence length
56 nt
GC content
0.2500

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-4.10 kcal/mol
Thermodynamic ensemble
Free energy: -5.80 kcal/mol
Frequency: 0.0630
Diversity: 19.79
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...........(((....(((((.((((..(....)..)))).)))))....))).
Thermodynamic Ensemble Prediction
.......,,,.{,,....(((((.{(((........}})))}.}))))},..}},.
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs showing altered expression in human skin tissue samples post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-3658 was not identified among the 545 differentially expressed microRNAs found in blood samples from monozygotic twin pairs, which were analyzed via microarray and validated by qRT-PCR to establish their potential for forensic discrimination [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].