Basic Information

Symbol
hsa-mir-367
RNA class
miRNA miRNA hairpin
Alias
MIR367 MicroRNA 367 Hsa-MiR-367-3p Hsa-Mir-367 MIRN367 Hsa-Mir-92-P2a_pre Hsa-MiR-367-5p MIMAT0000719 MIMAT0004686 MI0000775
Location (GRCh38)
4:112647874-112647941
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-367
Sequence length
68 nt
GC content
0.3529

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.10 kcal/mol
Thermodynamic ensemble
Free energy: -30.00 kcal/mol
Frequency: 0.2322
Diversity: 2.93
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
((((((((((((((((..(((((.((((.(........).}))).)))))..))))))))))))))))
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like the mir-367 showing altered expression patterns in human skin tissue post-burn and in hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-367 is involved in spermatogenesis, with predicted target genes including RUNX1, SMAD6, and LATS2, and functions in germ cell line proliferation and survival [Mawlah et al. DOI:10.5455/aim.2022.30.205-212]. Furthermore, a review noted that the mir-367 is differentially regulated by methylmercury in NT2 cell-derived cultures, where it targets axonal guidance pathways [Miguel et al. DOI:10.1089/Ars.2017.7175].