Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like the mir-367 showing altered expression patterns in human skin tissue post-burn and in hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-367 is involved in spermatogenesis, with predicted target genes including RUNX1, SMAD6, and LATS2, and functions in germ cell line proliferation and survival [Mawlah et al. DOI:10.5455/aim.2022.30.205-212]. Furthermore, a review noted that the mir-367 is differentially regulated by methylmercury in NT2 cell-derived cultures, where it targets axonal guidance pathways [Miguel et al. DOI:10.1089/Ars.2017.7175].