Basic Information

Symbol
hsa-mir-1225
RNA class
miRNA miRNA hairpin
Alias
MIR1225 MicroRNA 1225 Hsa-MiR-1225-5p Hsa-Mir-1225 MIRN1225 Hsa-MiR-1225-3p MIMAT0005572 MIMAT0005573 MI0006311
Location (GRCh38)
1:18897071-18897148
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1225
Sequence length
90 nt
GC content
0.7444

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-50.10 kcal/mol
Thermodynamic ensemble
Free energy: -50.80 kcal/mol
Frequency: 0.3193
Diversity: 7.83
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in human umbilical vein endothelial cells (HUVECs) demonstrated that the mir-1225 was significantly downregulated (fold change 9.17) in exosomes derived from cells under heat stroke temperature conditions, identifying it as a potential noninvasive biomarker for heat stroke [Chen et al. DOI:10.12659/MSM.909983]. In human denatured dermis from deep burn patients, the mir-1225 was significantly upregulated (11.61-fold) compared to paired normal skin, as validated by miRNA microarray analysis [Liang et al. DOI:10.1016/j.burns.2011.10.014].