Basic Information

Symbol
hsa-mir-369
RNA class
miRNA miRNA hairpin
Alias
MIR369 MicroRNA 369 Hsa-MiR-369-3p Hsa-MiR-369-5p Hsa-Mir-369 MIRN369 Hsa-Mir-154-P5_pre MIMAT0000721 MIMAT0001621 MIRN369-3 MI0000777 MIR369-3 Mir-369
Location (GRCh38)
14:101065598-101065667
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-369
Sequence length
70 nt
GC content
0.3714

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-28.10 kcal/mol
Thermodynamic ensemble
Free energy: -29.25 kcal/mol
Frequency: 0.1542
Diversity: 4.03
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((.((((((((((((((((..((((((............))))))..)))))))))))))))).))).
Thermodynamic Ensemble Prediction
.(((.((((((((((((((((..((((((..,....,,...))))))..)))))))))))))))).))).
Forensic Context

A study in humans demonstrated that the mir-369 was significantly down-regulated in the cord blood plasma of preterm newborns with culture-positive early-onset neonatal sepsis compared to gestational age-matched controls [Janec et al. DOI:10.14712/fb2023069050173]. A study in rats demonstrated that rno-miR-369-3p was significantly upregulated in myocardial tissue following burn injury, identifying it as a potential biomarker for myocardial damage [Guo et al. DOI:10.1080/09168451.2020.1807901]. In humans, the mir-369 was identified as a high diagnostic performance circulating microRNA that was up-regulated during acute myocardial infarction and subsequently declined after revascularization therapy [Wang et al. DOI:10.1186/s40364-024-00690-x].