Basic Information

Symbol
hsa-mir-371a
RNA class
miRNA miRNA hairpin
Alias
MIR371A MicroRNA 371a Hsa-MiR-371a-5p Hsa-Mir-371 Hsa-MiR-371a-3p MicroRNA 371 MIRN371 MIR371 Hsa-Mir-430-P5_pre Hsa-Mir-371a MIMAT0000723 MIMAT0004687 MI0000779
Location (GRCh38)
19:53787675-53787741
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-371a
Sequence length
67 nt
GC content
0.5224

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.20 kcal/mol
Thermodynamic ensemble
Free energy: -39.67 kcal/mol
Frequency: 0.4672
Diversity: 2.00
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in human cadavers demonstrated that exosomes and exosomal miRNAs, including the mir-371a-5p, are stably preserved in postmortem serum for at least three days when stored at or below 20°C [Kanno et al. DOI:10.1007/S00414-022-02913-Y]. Furthermore, bioinformatic analysis of human hypertrophic cardiomyopathy (HCM) plasma samples identified the mir-371a-5p as an upregulated miRNA component within a competing endogenous RNA network, predicted to target key hypoxia- and immune-related genes in HCM [Yu et al. DOI:10.1186/s40659-023-00451-4].