Basic Information

Symbol
hsa-miR-371a-5p
RNA class
miRNA mature miRNA
Alias
hsa-miR-371a MIR371A MicroRNA 371a
Location (GRCh38)
-
Forensic tag(s)
Postmortem interval inference Sudden cardiac death diagnosis
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-371a-5p
Sequence length
20 nt
GC content
0.5500
Forensic Context

A study in human cadavers demonstrated that exosomes and exosomal miRNAs, including the miR-371a-5p, are stably preserved in postmortem serum for at least three days when stored at or below 20°C [Kanno et al. DOI:10.1007/S00414-022-02913-Y]. Furthermore, bioinformatic analysis of human hypertrophic cardiomyopathy (HCM) plasma samples identified the miR-371a-5p as an upregulated miRNA component within a competing endogenous RNA network, predicted to target key hypoxia- and immune-related genes in HCM [Yu et al. DOI:10.1186/s40659-023-00451-4].