Basic Information

Symbol
hsa-miR-1225-5p
RNA class
miRNA mature miRNA
Alias
hsa-miR-1225 MIR1225 MicroRNA 1225
Location (GRCh38)
-
Forensic tag(s)
Cause of death analysis Wound age identification
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-1225-5p
Sequence length
22 nt
GC content
0.7727
Forensic Context

A study in human umbilical vein endothelial cells (HUVECs) demonstrated that the miR-1225-5p was significantly downregulated (fold change 9.17) in exosomes derived from cells under heat stroke temperature conditions, identifying it as a potential noninvasive biomarker for heat stroke [Chen et al. DOI:10.12659/MSM.909983]. In human denatured dermis from deep burn patients, the miR-1225-5p was significantly upregulated (11.61-fold) compared to paired normal skin, indicating its role in wound healing [Liang et al. DOI:10.1016/j.burns.2011.10.014].