Forensic Context

A study in humans demonstrated that the miR-374a-5p was significantly decreased in the plasma of male myocardial infarction patients compared to healthy controls, as identified by next-generation sequencing [Baulina et al. DOI:10.1016/j.yjmcc.2018.07.129]. A study in human monozygotic twins demonstrated that the miR-374a-5p was differentially expressed, being shared across three pairs of twins, which supports its potential role as a biomarker for distinguishing genetically identical individuals in forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].