Forensic Context

A study in Göttingen minipigs demonstrated that the miR-374b-5p was consistently down-regulated across all post-total body irradiation phases, identifying it as an early marker of lethal radiation [Chakraborty et al. DOI:10.1038/s41598-023-45250-9]. A review of radiation biomarkers noted that high expression of the miR-374b-5p in pre-treatment plasma was associated with shorter progression-free survival and lower local tumor control rates in head and neck squamous cell carcinoma patients [Jia & Wang DOI:10.3389/fcell.2022.861451].