Basic Information

Symbol
hsa-mir-374c
RNA class
miRNA miRNA hairpin
Alias
MIR374C MicroRNA 374c Hsa-MiR-374c-5p Hsa-MiR-374c-3p Hsa-Mir-374c MIMAT0018443 MIMAT0022735 MI0016684 Mir-374c
Location (GRCh38)
X:74218549-74218618
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Chronological age estimation Cause of death analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-374c
Sequence length
70 nt
GC content
0.4143

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-36.50 kcal/mol
Thermodynamic ensemble
Free energy: -37.07 kcal/mol
Frequency: 0.3967
Diversity: 1.89
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...((((.....((((((((((((((((((((......)))))))))))))))))))).....))))...
Thermodynamic Ensemble Prediction
.,.((((.....((((((((((((((((((((......)))))))))))))))))))).....)))).,.
Forensic Context

A study in mice demonstrated that serum mmu-miR-374c-5p expression was significantly decreased to 61% on day 1 specifically after lethal (10 Gy) total body irradiation, and its expression positively correlated with peripheral blood lymphocyte counts (r=0.6649) [Jia et al. DOI:10.1016/j.toxlet.2024.07.911]. In forensic transcriptome research, miR-374c-5p has been identified as one of several miRNAs used in an age prediction model from human bloodstains [Haas et al. DOI:10.1016/j.fsigen.2021.102486].