Basic Information

Symbol
hsa-mir-1226
RNA class
miRNA miRNA hairpin
Alias
MIR1226 MicroRNA 1226 Hsa-MiR-1226-3p Hsa-MiR-1226-5p Hsa-Mir-1226 MIRN1226 MIMAT0005577 MIMAT0005576 MI0006313 Mir-1226
Location (GRCh38)
22:45200954-45201019
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1226
Sequence length
75 nt
GC content
0.6400

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-35.40 kcal/mol
Thermodynamic ensemble
Free energy: -36.85 kcal/mol
Frequency: 0.0957
Diversity: 6.75
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...((((.(((((((.((((.((((((.((((((....))).....))).)))))))))).))))))).))))..
Thermodynamic Ensemble Prediction
...((((.(((((((.((((.((((((.{(({({....})),....})).)))))))))).))))))).))))..
Forensic Context

A study in humans identified the mir-1226 as upregulated in denatured dermis compared to paired normal skin four days post-burn, with a 14.09-fold increase [Liang et al. DOI:10.1016/j.burns.2011.10.014]. A subsequent review confirmed the mir-1226 is upregulated four days post-burn in deep partial thickness burn skin versus normal skin [Siu et al. DOI:10.1111/wrr.13100].