Basic Information

Symbol
hsa-mir-376a-1
RNA class
miRNA miRNA hairpin
Alias
MIR376A1 MicroRNA 376a-1 Hsa-MiR-376a-3p Hsa-MiR-376a-5p Hsa-Mir-376a-1 Hsa-Mir-376a MIRN376A1 MIRN376A Hsa-Mir-376-P1_pre MicroRNA 376a MIMAT0000729 MIMAT0003386 MIRN376A-1 Mir-376a-1 MIR376A-1 MI0000784 hsa-mir-376a
Location (GRCh38)
14:101040782-101040849
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-376a-1
Sequence length
68 nt
GC content
0.2941

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-18.20 kcal/mol
Thermodynamic ensemble
Free energy: -19.83 kcal/mol
Frequency: 0.0714
Diversity: 6.97
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.((((.((.((((.((({{((((((...{((,....})),,...)))))))))).)))).)).)))).
Forensic Context

A study in humans demonstrated that plasma-derived exosomes from severe trauma patients exhibit significant downregulation of 60 microRNAs, including 12 with direct roles in hematopoiesis, compared to operative controls [Munley et al. DOI:10.1097/TA.0000000000004225]. A study in rhesus macaques demonstrated that the mir-376a-1 was utilized as a feature in a dose-prediction model at Day 9 and in a pleural effusion prediction model at Day 6 [May et al. DOI:10.1038/s41598-022-16316-x].