Basic Information

Symbol
hsa-miR-376a-3p
RNA class
miRNA mature miRNA
Alias
hsa-miR-376a MIR376A MicroRNA 376a
Location (GRCh38)
-
Forensic tag(s)
Cause of death analysis
External database

Sequence & Structure

Transcript ID
hsa-miR-376a-3p
Sequence length
21 nt
GC content
0.3810
Forensic Context

A study in Göttingen minipigs demonstrated that the miR-376a-3p is an early marker of lethal radiation, being consistently down-regulated across all post-total body irradiation phases and linked to carcinogenesis [Chakraborty et al. DOI:10.1038/s41598-023-45250-9]. In a separate investigation using Sprague–Dawley rats, the miR-376a-3p was found to be upregulated in lung tissue at 24 hours after burn injury, with a fold change of 2.6, and was associated with inflammation and apoptosis pathways [Zhang et al. DOI:10.5505/tjtes.2018.98123].