Forensic Context

A study in mice demonstrated that the mir-376a is upregulated in serum at 3 hours post-mild traumatic brain injury across injury severities, identifying it as a potential biomarker for mild TBI [Martinez & Peplow DOI:10.4103/1673-5374.219025]. A systematic review and meta-analysis in humans reported the mir-376a as a diagnostic marker for severe TBI from cerebellar tissue, contributing to the overall high diagnostic accuracy of miRNAs for TBI [Zhou et al. DOI:10.7150/ijms.48214].