Basic Information

Symbol
hsa-mir-376b
RNA class
miRNA miRNA hairpin
Alias
MIR376B MicroRNA 376b Hsa-Mir-376b Hsa-MiR-376b-3p MIRN376B Hsa-Mir-376-P2_pre Hsa-MiR-376b-5p MIMAT0022923 MIMAT0002172 MI0002466 Mir-376b
Location (GRCh38)
14:101040436-101040535
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-376b
Sequence length
100 nt
GC content
0.3500

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-33.60 kcal/mol
Thermodynamic ensemble
Free energy: -36.06 kcal/mol
Frequency: 0.0183
Diversity: 8.22
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((.....(((((((((.(((((((((((.(((((.(((((...((..........))....)))))))))).))))))))))).))))))))).))))
Thermodynamic Ensemble Prediction
{(({.....(((((((((.(((((((((((.(((({{(((((.{,((..,....,..)).)}.)))))))))).))))))))))).))))))))).))))
Forensic Context

A study in rats demonstrated that the mir-376b was down-regulated more than 1.5-fold in the hippocampus at 1, 3, and 5 days following controlled cortical impact injury, identifying it as a potential marker for traumatic brain injury progression [Sun et al. DOI:10.1007/s11596-014-1313-1]. In a separate investigation in Sprague-Dawley rats, the mir-376b was upregulated 2.62-fold in the corpus cavernosum of obese rats with erectile dysfunction, and its expression was validated by real-time PCR [Bai et al. DOI:10.1016/j.esxm.2017.06.006].