Basic Information

Symbol
hsa-mir-378b
RNA class
miRNA miRNA hairpin
Alias
MIR378B MicroRNA 378b Hsa-Mir-378b Hsa-MiR-378b MIMAT0014999 MI0014154
Location (GRCh38)
11:59595077-59595158
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden death from CNS diseases
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-378b
Sequence length
57 nt
GC content
0.5088

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-26.40 kcal/mol
Thermodynamic ensemble
Free energy: -26.57 kcal/mol
Frequency: 0.4583
Diversity: 2.81
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((.((..(((((((((.((((((.......)))))).)))))))))..)).))))
Thermodynamic Ensemble Prediction
((((.((..(((((((((.((((((.......)))))).)))))))))..)).))))
Forensic Context

A study in miniature Yucatan pigs demonstrated that serum miR-378b-3p showed high diagnostic accuracy for differentiating spinal cord injury from SHAM groups (AUC = 0.90), severe from mild SCI (AUC = 0.92), and moderate from mild SCI (AUC = 0.79) [Tigchelaar et al. DOI:10.1038/s41598-017-01299-x].