A study in humans identified the mir-1226 as upregulated in denatured dermis compared to paired normal skin four days post-burn, with a 14.09-fold increase [Liang et al. DOI:10.1016/j.burns.2011.10.014]. A subsequent review confirmed the mir-1226 is upregulated four days post-burn in deep partial thickness burn skin versus normal skin [Siu et al. DOI:10.1111/wrr.13100].