Basic Information

Symbol
hsa-mir-378d-1
RNA class
miRNA miRNA hairpin
Alias
MIR378D1 MicroRNA 378d-1 Hsa-Mir-378d-1 Hsa-MiR-378d MIMAT0018926 Mir-378d-1 MI0016749 hsa-mir-378d
Location (GRCh38)
X:11318614-11318686
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification Cause of death analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-378d-1
Sequence length
54 nt
GC content
0.4074

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-19.80 kcal/mol
Thermodynamic ensemble
Free energy: -20.32 kcal/mol
Frequency: 0.4292
Diversity: 2.70
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((((((((((..((((..((.......)).))))..)))..))))))))).
Thermodynamic Ensemble Prediction
.((((((((((((..((((..({.......)}.))))..)))..))))))))).
Forensic Context

A study in humans demonstrated that the mir-378d is differentially expressed in blood samples from monozygotic twins, where it was shared across two pairs of twins in a microarray analysis [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003]. Another study in humans found that the mir-378d was downregulated in serum exosomes from patients with sepsis and septic shock compared to healthy controls [Li et al. DOI:10.1038/s41598-025-89946-6].