Basic Information

Symbol
hsa-mir-379
RNA class
miRNA miRNA hairpin
Alias
MIR379 MicroRNA 379 Hsa-MiR-379-3p Hsa-MiR-379-5p Hsa-Mir-379 MIRN379 Hsa-Mir-154-P7_pre MIMAT0004690 MIMAT0000733 MI0000787 Mir-379
Location (GRCh38)
14:101022066-101022132
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis Cause of death analysis Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-379
Sequence length
67 nt
GC content
0.4179

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-26.30 kcal/mol
Thermodynamic ensemble
Free energy: -27.28 kcal/mol
Frequency: 0.2040
Diversity: 2.76
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that hsa-miR-379 is upregulated in burn hypertrophic scar (HS) tissue and its derived fibroblasts compared to normal skin and fibroblasts [Siu et al. DOI:10.1111/wrr.13100]. Another human study identified hsa-miR-379-5p as significantly decreased in pericardial-fluid-derived exosomes from acute myocardial infarction cases compared to controls, highlighting its potential as a postmortem diagnostic biomarker [Kim et al. DOI:10.3390/ijms25179619]. A study in mice demonstrated that the mir-379 was differentially expressed after 56Fe ions irradiation in blood [Jia et al. DOI:10.3389/fcell.2022.861451]. In rats, the mir-379 was downregulated in penis tissue in age-related erectile dysfunction models [Song et al. DOI:10.3389/fendo.2022.1034043].