Basic Information

Symbol
hsa-mir-380
RNA class
miRNA miRNA hairpin
Alias
MIR380 MicroRNA 380 Hsa-MiR-380-5p Hsa-Mir-380 Hsa-MiR-380-3p MIRN380 Hsa-Mir-154-P8_pre MIMAT0000734 MIMAT0000735 MIR380-3p MI0000788 Mir-380
Location (GRCh38)
14:101025017-101025077
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-380
Sequence length
61 nt
GC content
0.4098

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-24.50 kcal/mol
Thermodynamic ensemble
Free energy: -25.52 kcal/mol
Frequency: 0.1903
Diversity: 3.64
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((...(((((((..(((((((.(((....))).)))))))..)))))))..))))))
Thermodynamic Ensemble Prediction
{(((((...(((((((..(((((((,{{{....}}).)))))))..)))))))..)))))}
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific dysregulation patterns observed in human skin tissue and cell lines post-thermal injury [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-380 is among miRNAs uniquely detected in semen fluids [Alsaeed et al. DOI:10.1007/s12024-024-00831-6]. A separate comprehensive characterization of small RNA profiles in forensic stains confirmed the mir-380 is reported in published data as a potential marker for semen [Liu et al. DOI:10.3390/genes13091530].