A study in humans identified the miR-380-3p as a potential biomarker predicted to bind hsa_circRNA_103899, a circRNA that is up-regulated in sepsis-induced acute respiratory distress syndrome (ARDS) [Guo et al. DOI:10.1016/j.lfs.2021.119566]. A study in mice demonstrated that the miR-380-3p is among the 50 most down-regulated miRNAs after traumatic brain injury (TBI) [Meissner et al. DOI:10.1089/neu.2015.4077].