Basic Information

Symbol
CRABP1
RNA class
mRNA
Alias
Cellular Retinoic Acid Binding Protein 1 CRABP-I Cellular Retinoic Acid-Binding Protein 1 CRABPI CRABP RBP5 Cellular Retinoic Acid-Binding Protein I
Location (GRCh38)
15:78340260-78348250
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_004378.3
Sequence length
738.0 nt
GC content
0.5718

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-241.00 kcal/mol
Thermodynamic ensemble
Free energy: -253.70 kcal/mol
Frequency: 0.0000
Diversity: 199.29
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((..(((..(((.((....((.((((..((.(((....))).))..))))))...)))))((..((((.....(((((.((((.....(((((..((((((.((((((((((..(........)..))))))((((((.(((((.(((....((.......)).(((((((.((.((((((.......))))))))((((((((((.((.....)))))))...)))))....((((.(((..(((..(((((.((((.(...((..((((((((((......))))))))))..))..).))))...).)))).)))..))))))).)))))))(((((((((.((....(.(((((((((.((...(((((((((((((..((((..(((........)))..))))((((.(((((.(..(..((((.((..(((((((((.((.(((......))).)).)))).....))))).))))))..)....).))))).))))...)))))))))))))...((((....)))).(((((........)))))..)))).))))))).).......((.((((.......)))).)))).)))))))))(((.(((....))).)))...........)))..))))))))))))))).)))).....))..)))))....)))).))))).....))))..)).(((......)))))).)))).........
Thermodynamic Ensemble Prediction
.((((,,(((..(((.((.{{{,{,((((.,((.(((..,,}||.}}.,}}}}}}|,.))})}((,.((((.,...(((((.((((.....(((((..(({{((,((((((({((,,(....,,,.)..)))))}((((((.(((((.(((..,{{{{,,.|..,,,.|))))},||.((((((.......))))))},((((,{{{||,|,.,,..|||||}|,..,{|||,...{(((.(((..(((..(((({.((((.|...((..((((((((((......))))))))))..))..,.))))...}.)))}.)))..))))))}.},}}}},(((((((((.((....{.(((((((({.((,..(((((((((((((,,((((..(((........)))..))))((((.(((((.{..{,.{(((.{{{.(((((((((.((.(((......))).)).)))),....})))).)}))))..,,.,.}.))))).)))),,.))))))))))))).,}|{(({{{.,}}}.(((((........)))))}}))))}})))))).}.......,,.{{((.......}))),).)).))))))))),,|,,,..}}.}))})))}}),)},,,..)))..)))))))))))}}}}.}}},...,,}}..)))))....)))).)))))..,..))))..}}.(({......)))))}.)))).........

Transcripts

ID Sequence Length GC content
NM_004378.3 NCBI
AGUCUCCGCCUUGCGAGCUCAGAGUGUGCCCGCUGCGCCGCCGCUGUCC… 738 nt 0.5718
Summary

This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008]

Forensic Context

A study in human skin wound healing identified the CRABP1 as a marker for hair follicle-adjacent fibroblast clusters within the dermis using spatial transcriptomic sequencing [Liu et al. DOI:10.1016/j.stem.2024.11.013].