The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and activation of the transcription factor ELK1. [provided by RefSeq, Jul 2008]
Forensic Context
A study in human trauma patients demonstrated that the DEPP1 mRNA was significantly downregulated in circulating CD3+ T cells during the injury stage compared to the recovery stage [Rau et al. DOI:10.2147/JIR.S375881].