Basic Information

Symbol
DPPA5
RNA class
mRNA
Alias
Developmental Pluripotency Associated 5 Esg1 Developmental Pluripotency-Associated 5 Protein Embryonal Stem Cell-Specific Gene 1 Protein Embryonal Stem Cell Specific Gene 1 HDPPA5 ESG-1 ESG1
Location (GRCh38)
6:73353063-73354276
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001025290.3
Sequence length
659.0 nt
GC content
0.4841

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-230.40 kcal/mol
Thermodynamic ensemble
Free energy: -241.29 kcal/mol
Frequency: 0.0000
Diversity: 118.51
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.....((((((((((((((((((((.(((((((.(((..(((((((.......(((((((((((((((..(((....)))...)))).))).))..))))))....(((((...(((...((((.((((.((((((...((.(((((..((((....)))))))))))...)))))).)))).))))..)))...)))))(((((......)))))((((((((((((....)))))))))..)))..((((((((((((((.((((........((((..(((((((..(..((((.((((((((((...))))).).))))))))..)..)).)))))....).)))........)))))))))))))....))))).....))))))).))).)))...)))).))))))))....))))....)))))))).((((((((((((((.(((..(((((.(((......))).)))))............))).))))))))....(((((((((.........)))))))))(((((((((((....)))))))))))...................))))))...(((((((...(((((((...............))))))).....)))))))...................
Thermodynamic Ensemble Prediction
.....{(((((((((((((((((((.(((((((.(((..(((((((......,(((((((((((((((..({{....}}}...)))).))).),.})))))),...{{(((...(((,,,((({.((((.((((((...(,{((,,({{((((....}))))))))))...)))))).)))).||||..}||,,,|||||{{{{,..,,,.)))))||{{{{||||||,,,,)))))))))..))}..((((((((((((((.((((........{{{{..(((((((..{..((((.(((({(((((...))))).}.))))))))..}..)).)))))..,.,.}}).,......)))))))))))))....))))).....))))))).))).)))...)))).))))))))....))),...,)))))))}.({{{{{((((((((.(({,{(((((.(((......))).)))},.........,}}))).)))))))}....(((((((((.........)))))))))(((((((((((....)))))))))))..,,||{,,,,,,,..,..|}||||...{((((({..,((((({(...............)))))))...,.))))))),,.................

Transcripts

ID Sequence Length GC content
NM_001025290.3 NCBI
GAUUAGGCCUGGUUUGCGCUGGAGAGUGGUCUUGGUUGUGAGGGUCAUA… 659 nt 0.4841
Summary

This gene encodes a protein that may function in the control of cell pluripotency and early embryogenesis. Expression of this gene is a specific marker for pluripotent stem cells. Pseudogenes of this gene are located on the short arm of chromosome 10 and the long arm of chromosomes 14 and 19. [provided by RefSeq, Dec 2010]

Forensic Context

A study in human menstrual blood-derived mesenchymal cells (MBMCs) demonstrated that reprogramming to induced pluripotent stem cells (iPS-MBMCs) was rapid and efficient, with robust transcript levels of the pluripotency marker DPPA5 detected in the established iPS-MBMC lines [de Carvalho Rodrigues et al. DOI:10.3727/096368912X653048].