Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq, Jul 2008]
Forensic Context
A study in human and rat corpus cavernosum identified the DPT as a universal marker of human corpus cavernosum fibroblasts, where it was diffusely expressed across steady-state fibroblasts [Yin et al. DOI:10.1016/j.celrep.2024.114760].