Basic Information

Symbol
ERH
RNA class
mRNA
Alias
ERH MRNA Splicing And Mitosis Factor DROER Enhancer Of Rudimentary Homolog Enhancer Of Rudimentary (Drosophila) Homolog Enhancer Of Rudimentary Homolog (Drosophila)
Location (GRCh38)
14:69380123-69398334
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_004450.3
Sequence length
791.0 nt
GC content
0.4235

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-197.70 kcal/mol
Thermodynamic ensemble
Free energy: -216.48 kcal/mol
Frequency: 0.0000
Diversity: 274.04
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((.(((((((((..((.((((((((.((....)).)))))))).)).....)))))))))))))).(((((((...(((..(((((((((((((((.....(((....))).....((((((....((((((((((((........)))))).....))))))....))))))....(((((....)).)))((((((..((((.(.((((.((((..((((....))))..((((((...((((((..((((.(((((.......))))).))))...)))..)))....))))))..(((((((............((((((........))))))(.((((........)))).)......)))))))........)))).)))).).))))..))))))..))))))))(((((.((((((((((((((...(((........))).))))).)))).....))))))))))(((.((((.....)))).))).......)))))))..))).))))))).............(((.((((((..((((((.((((................................((((((....((((((.......((((....))))))))))...))))))((((..(((........((((.(((.......))))))).......))))))).......)))).))))))))))))(((.((((......).))).)))(((((((...)))))))................)))..........
Thermodynamic Ensemble Prediction
{((((.(((((((((.{((.((((((((.((....)).)))))))).)),....)))))))))}))}|.,{{(((,{{{{((((.((((.{{((.{,.....,.{{{....))),.....,..)))))))}}}}...||||,,,{...,|||{((((({((({(({.{{{(((((((({{{(,,((({.{{,.,{{({((((((..,((((({{..(((..((((....))))..))}.{{{{...,|||{{(,(((((,,{...{{{{||,,,{{{....})))}})))...})))))},.((((.(((......))).)))).....{((,..,.))}..(((((((..((.{{{....((((......))))......,}}))..)),})))),)))))})))))))}{((({,(((((({(((((.{.((((.{((((((.(((.({...,).))).)))))}...)))).,,))))}})},....,,,}|}|,{{{{{{{,,,....{((.((({...(((((....{{...,.{((......)))..}),)))))..}}))..))),.,,,.,..............,{{{((((....,}|||{,,,}|{||{{{|.,.,,)))))))}...}}}}}}})}}}}}}}}}.})}.})}}}}}.,,.,.}})))),,)))),,,.,,|.,||||||||.,,))),))}))}|||.||(({.{,{,......,)))).)))|((((((...))))))}..........,,,,.....,,},.,,,..

Transcripts

ID Sequence Length GC content
NM_004450.3 NCBI
GUUGUAGUUAAGCUCGUGUAACGGCGGCGGUGUCGGCAGCUGCUGUAGC… 791 nt 0.4235
Summary

Enables methyl-CpG binding activity. Predicted to be involved in pyrimidine nucleoside metabolic process. Located in midbody and nucleus. Part of methylosome. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that the protein ERH binds DGCR8 and may assist its dimerization to promote the processing of suboptimal miRNAs within clusters [Shang et al. DOI:10.1038/s41576-023-00611-y].