Basic Information

Symbol
AHSP
RNA class
mRNA
Alias
Alpha Hemoglobin Stabilizing Protein EDRF ERAF Erythroid Differentiation-Related Factor Alpha Hemoglobin Stabilising Protein Alpha-Hemoglobin-Stabilizing Protein Erythroid Differentiation Associated Factor Erythroid Associated Factor Erythroid-Associated Factor
Location (GRCh38)
16:31527876-31528803
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016633.4
Sequence length
488.0 nt
GC content
0.5287

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-171.50 kcal/mol
Thermodynamic ensemble
Free energy: -180.84 kcal/mol
Frequency: 0.0000
Diversity: 86.83
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((.(((..((((.(((.((....)).))).))))......(((((((((...(((.(((((((((((((((........))))).........(((..(((...))).)))(((((....(((.(((((((...)))))))((((((..(((......)))..)))))).....((.((.(((((((((..((.((((......))))..))..))))))))).)).))((((((..((((((((..(((((........)))))...))...((((((....)))))).(((.((((((.........)))))))))...(((((((....)))))))....))))))..))))))...)))....)))))..((((((((............))))))))....)))).)))))).)))..)))))))))))))))..................(((((((.(((((....)))))))))))).
Thermodynamic Ensemble Prediction
.(((,(((..{{{{.(((.{|,...|},)}),)))||.....{((((((((...(((.(((((((((((((({,{....,,)))))....(((.......))).,{{{|..,.{((((,{{{(({..,{||||},,||,||,{((((((..(((......)))..)))})),,,,.||.||,(((((((((..((.((((......))))..))..))))))))){|,,,,((((((..(((((({{..(((((........)))))...}}.|.((((((....)))))).{((.((((((.........))))))))}.,,(((((((....))))))).,}.))))))..))))))..,,)),}}})))))..((((((((............))))))))....)))).)))))).)))..))))))))}}}}}))...}}},...,,,.....{((((((((((((....)))))))))))).

Transcripts

ID Sequence Length GC content
NM_001318221.2 NCBI
ACAGAGAGAUUCACGCACCCUCAAGAGUGUGGGUGAGACAUAUACAGCC… 484 nt 0.5269
NM_001318222.2 NCBI
GGAAAAUCGUGACCUCAGAGCAGGGCAGGAUGUGAAAGGCAGAUGGCUC… 463 nt 0.5335
NM_016633.4 NCBI
ACAGAGAGAUUCACGCACCCUCAAGAGUGUGGGUGAGACAUAUACAGCC… 488 nt 0.5287
Summary

This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Forensic Context

No relevant information is available at the moment.