F-Box And Leucine Rich Repeat Protein 16
C16orf22
Fbl16
F-Box/LRR-Repeat Protein 16
MGC33974
F-Box And Leucine-Rich Repeat Protein 16
Chromosome 16 Open Reading Frame 22
C380A1.1
FBL16
Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Forensic Context
A study in humans established a targeted RNA sequencing protocol for predicting the time-of-day of bloodstain deposition, where the FBXL16 was quantified as one of 69 candidate mRNA markers [Gosch et al. DOI:10.1101/2025.02.03.636230].