Basic Information

Symbol
FDCSP
RNA class
mRNA
Alias
Follicular Dendritic Cell Secreted Protein FDC-SP C4orf7 Follicular Dendritic Cell Secreted Peptide FDC Secreted Protein Chromosome 4 Open Reading Frame 7
Location (GRCh38)
4:70226124-70235252
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_152997.4
Sequence length
513.0 nt
GC content
0.3860

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-92.30 kcal/mol
Thermodynamic ensemble
Free energy: -105.05 kcal/mol
Frequency: 0.0000
Diversity: 114.38
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
............((((((.((((((((((((.(((..((((((..((..(.(......).)..))..)))))).))))))))(((.((((...)))).))))))))))..((((..((((....))))..)))).))))))(((((((.((((.((((((.(((.......((((((((......(((......))).........................((((((.(((((..((....(((.((((((..(((..(((((((((((........)))).................(((....((.....))....))).)))))))...))).)))))))))....))))))).).)))))........)))))))).......))).))))))....................(((((..(((.............))).)))))........))))))))))).........((((.((((...)))).))))..............
Thermodynamic Ensemble Prediction
.,..,,,,,...((((((.((((((((((((.(((..((((((..((..,.(......).,..))..)))))).))))))))(((.((((...}))).)))))))))){,((((..((((....))))..))))})))))}{{{{{{{,{{{{,(({{{(,(({,......{{{{((((......{,{..,....,,...........,,},..........((((({.(((((..{(....(((.((((((..(((..(((((((.{{{........},,|,,,...............,.....}|},...)),....,}.)))))))...))).)))))))))....})))))).)})}))).,......}}}}))))..,,,,.|||,}||||.....,,{,...,,.,,.{,.,{{({..,.({.....}},,,..,,}.}}}}}..,.}},,))))))))))).........{{{{.{{{,.,.}))),))))..............

Transcripts

ID Sequence Length GC content
NM_152997.4 NCBI
AGUCACUUGCCAUUUCUCAUAACAGCGUCAGAGAGAAAGAACUGACUGA… 513 nt 0.3860
Summary

This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion. [provided by RefSeq, Dec 2011]

Forensic Context

A study in humans demonstrated that the mRNA marker FDCSP is a saliva-specific gene, as a novel RT-LAMP CRISPR-LFA assay detected its expression exclusively in saliva samples (7/7) with no cross-reactivity to blood, semen, or vaginal fluids [Su et al. DOI:10.1007/s12024-025-01079-4].