This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Forensic Context
A multi-omics study in human postmortem prefrontal cortex (Brodmann Area 9) identified widespread transcriptomic and epigenomic alterations in cocaine use disorder, with ZFAND2A being the only transcriptome-wide significantly upregulated gene [Zillich et al. DOI:10.1038/S41398-024-03139-9].