Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in humans identified FOXD4L6 as a key hub gene within a protein-protein interaction network constructed from differentially expressed mRNAs in the ceRNA regulatory network of septic acute kidney injury, based on RNA-seq analysis of whole blood from patients and healthy controls [Ma et al. DOI:10.3389/fgene.2023.1209042].