Enables amyloid-beta binding activity; scavenger receptor binding activity; and signaling receptor activity. Involved in several processes, including cellular response to amyloid-beta; positive regulation of ERK1 and ERK2 cascade; and regulation of defense response. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in mice demonstrated that the FPR2 is a promising marker for thrombus age estimation, as its expression was time-dependently up-regulated after deep vein thrombosis induction [Huang et al. DOI: 10.007/s12024-024-00818-3].