Basic Information

Symbol
GKN1
RNA class
mRNA
Alias
Gastrokine 1 AMP18 CA11 BRICD1 18 KDa Antrum Mucosa Protein BRICHOS Domain Containing 1 Gastrokine-1 Protein CA11 Foveolin AMP-18 FOV
Location (GRCh38)
2:68974573-68980980
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_019617.4
Sequence length
753.0 nt
GC content
0.4250

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-203.30 kcal/mol
Thermodynamic ensemble
Free energy: -218.39 kcal/mol
Frequency: 0.0000
Diversity: 256.37
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((.(((...(((...((((.........((((((((((..(((...)))...))))))))))((((.((((.(((((((((((.(((.((((((..(((..(............((((....))))............)..))))))))).)))..((...((((((((.((..(((...)))..)).))))))))...))...))).)))))))).)))).))))....))))...)))...)))((((.((((..((...(((((.....)))))..)).....))))))))..((((((((((((((((((((...(((....(((((((......)))))))....))).....)))))).....((.(((((....)))))...))((((..((((((((((((............((.((((((((.(((((((.......))).))))...)).).))))).)).............))))))))....))))..))))...((((..........))))..((((.(((((.....))))).))))((((((.....(((((..(((((....))))).))))).....))))))........(((...)))((((((....))))))..((((((.(((((((...((((.....(((((....))))).....))))...))))))).))).)))......))))))))))..))))..............)))))....
Thermodynamic Ensemble Prediction
.((((,((({{{(((,,,((((({.......|||{{|||{{,.,((,,,|||{{,,}}}}})))}}}}}}|||,.(((({({.,,,,|||}|,((,{.,{{,..,............((({....)))).........,.,)}.}))))))))}),|{{((,..((((((((.((..(((...)))..)).))))))))...},..,(({(((|||{{|.|)).}))))}}}}||||,,,|||...|||{{{{,{{{,.,}|,..(((({.....)))}}..||{.,,,}}}}.....|{,{|||{{|||||||{{|{(||,{,(,,{,({{(({(,,,.,,}|}}}}}....}}}.,,,,}||}}}.|||,||.(((((....)))))...||{,|({{{,..,{||||||.}}}.......,|,,,||||,|||({{,{{{,,.....,,}.}}}}...(((((((.{(((....))}.,))))))).{{|||,,{{.,.|{.|||,...)}},}},,}},.}})))},,|{{{,{{(({,,,,,))))).}}})||||||,,,..(((((..(((((....))))).))))).....}}}}}}...{{{,.(({...})),|||||,,,}},||((({((((((.(((((((.,.{(((.....(((((....))))).....})),...))))))).))).))},))))})|||||}}||..},,,,,...,,,,,....}})))}},.

Transcripts

ID Sequence Length GC content
NM_019617.4 NCBI
AUGCUUGCCUACUCCUCUGUCCACUGCUUUCGUGAAGACAAGAUGAAGU… 753 nt 0.4250
Summary

The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008]

Forensic Context

A study in humans demonstrated that the GKN1 mRNA is used in targeted massively parallel sequencing assays for the identification of stomach tissue [Haas et al. DOI:10.1016/j.fsigen.2021.102486].